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The expression and significance of VEGF-C and VEGF-D in nasopharyngeal carcinoma

Wenqing Liu

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Abstract

Objective To explore the expressions of VEGF-C and VEGF-D and the correlation with the metastasis through the lymphatic system in nasopharyngeal carcinoma.Method VEGF-C and VEGF-D were labeled by improved immunohistochemical method(S-P), and the relation between their expressions and biological characteristics of nasopharyngeal carcinoma was studied.Result Expressions of VEGF-C and VEGF-D were related to the tumor metastasis through the lymphatic nodes.Conclusion VEGF-C and VEGF-D can regulate the lymphangiogenesis of nasopharyngeal carcinoma and provide scientific theoretical arguments for the therapy of anti-lymphangiogenesis in nasopharyngeal carcinoma patients.

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What this paper is about

Objective To explore the expressions of VEGF-C and VEGF-D and the correlation with the metastasis through the lymphatic system in nasopharyngeal carcinoma.Method VEGF-C and VEGF-D were labeled by improved immunohistochemical method(S-P), and the relation between their expressions and biological characteristics of nasopharyngeal carcinoma was studied.Result Expressions of VEGF-C and VEGF-D were related to the tumor metastasis through the lymphatic nodes.Conclusion VEGF-C and VEGF-D can regulate the lymphangiogenesis of nasopharyngeal carcinoma and provide scientific theoretical arguments for the therapy of anti-lymphangiogenesis in nasopharyngeal carcinoma patients.

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Available abstract

Objective To explore the expressions of VEGF-C and VEGF-D and the correlation with the metastasis through the lymphatic system in nasopharyngeal carcinoma.Method VEGF-C and VEGF-D were labeled by improved immunohistochemical method(S-P), and the relation between their expressions and biological characteristics of nasopharyngeal carcinoma was studied.Result Expressions of VEGF-C and VEGF-D were related to the tumor metastasis through the lymphatic nodes.Conclusion VEGF-C and VEGF-D can regulate the lymphangiogenesis of nasopharyngeal carcinoma and provide scientific theoretical arguments for the therapy of anti-lymphangiogenesis in nasopharyngeal carcinoma patients.

Key concepts: Lymphangiogenesis, Nasopharyngeal carcinoma, VEGF receptors, Medicine, Lymphatic system, Immunohistochemistry, Metastasis, Internal medicine

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