Transurethral Photoselective Vaporization of the Prostate with Large-Volume Benign Prostate Hyperplasia

Objective To investigate the efficacy and safety of 80Watt high-power potassium-titanyl-phosphate (KTP)photoselective laser vaporization of the prostate(PVP)in patients with large-volume benign prostate hyperplasia(100mL).Methods Retrospective analysis was performed in patients with large-volume benign prostatic hyperplasia(100mL),who were treated with the 80Watt KTP transurethral photoselective laser vaporization of the prostate from September 2007to November 2009.The preoperative evaluation included prostate volume by transrectal ultrasonic scanning,serum sodium and serum hemoglobin,international prostate symptom score(IPSS)and quality of life(QOL)score.The operative time and vaporization energy and average indwelling catheterization time were recorded.The postoperative serum sodium,serum hemoglobin after the operation were compared with those before the operation.After 3months,the IPSS,QOL and residual prostate volume were evaluated.Results Forty-five patients of totally 219patients with100mL prostate in volume were successfully operated under continuous epidural anesthe-sia.None was changed to open operation.The mean preoperative prostate volume was(128.82±24.82)mL,the mean IPSS was(27.10±2.88)and QOL were(4.26±0.87).The mean operative time was(141.00±30.19)minutes.The mean indwelling catheterization was(102.17±19.50)hours.The serum sodium did not change,while the serum hemoglobin level reduced mildly but without transfusion.After 3month,the mean IPSS was(11.58±2.52) and QOL were(2.74±1.10)with residual prostate volume was(44.63±10.31)mL.No stricture was observed in this group.Conclusion The transurethral photoselective vaporization of the prostate with 80Watt KTP laser is a safe and effective therapy for patients with100mL prostate in volume in experienced PVP center.