Clinical Observation on Therapeutic Effect and Safety of Photoselective Vaporization of Prostate in Treatment of Large Prostate (Report of 82 Cases)

Objective To study the safety and effectiveness of photoselective vaporization of prostate (PVP) in treatment of large prostate with volume more than 100 ml. Methods Retrospective analysis was performed in 82 benign prostatic hypertrophy (BPH) patients undergoing the PVP treatment,whose prostate volmue was more than 100ml. Results Average prostatic volume in all cases was 176 (110~340)ml. The operation in 77 cases was successfully completed in one time. But in other 5 cases,the twice operation was performed. In all cases,the dysuria symptom improved noticeably. International prostate symptom score (IPSS) and quality of life score (QOL) decreased from preoperative 27.5and 4.6 to postoperative 8.4 and 2.1,respectively. Maximal urinary flow rate (Qmax) increased from 4.9ml/ s to 19.0ml/s,and residual urine volume (RUV) decreased from 350ml to 110ml. IPSS,QOL,Qmax and RUV were significantly improved,compared with preoperative data(P0.01). Conclusion PVP is believed to be a safe and efficacious surgical method in treatment of large prostate with volume more than 100ml.