Lornoxicam combined with propofol: applicate for painless artificial abortion

Objective:To investigate the analgesic efficacy of lornoxicam combined with propofol on pain followed by artificial abortion. Methods:Ninety patients were divided into three groups randomly to receive different anesthetics: propofol alone(group D);propofol and 1μg/kg of fentanyl(group DF);lornoxicam 16mg and propofol(group DL).VAS(visual analogue score) as the index of pain intensity,was recorded at five time-points: 0,5,10 and 20 minutes after patients recovering anesthesia and the patients left hospital.The degree of body motion during operation,the summed propofol,awake time and orientation recovery time were observed.Results:VAS was not different between group DF and group DL,but VAS in both groups were lower than in group D.VAS at 20 minutes and when patients left hospital were lower in group DL than in group DF.Compared with in group D and group DL,the degree of body motion was lighter,the summed propofol smaller,awake time and orientation recovery time shorter in group DF.Compared with pre-anesthesia,SBP,DBP,HR,SpO2 after anesthesia were lower in group DF.The ratio of bradycardia and respiration depression were more serious in group DF than that of other two groups.Conclusion: Lornoxicam combined with propofol could control the pain followed by artificial abortion,but the analgesic efficacy during operation is not sufficient.