2011•Chinese Journal of Clinical Rational Drug UseRequires access

Clinical application of lornoxicam combined with propofol in painless abortion operation

Yang Li-jia

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Abstract

Objective To observe the safety and reliability of lornoxicam combined with propofol in painless abortion operation.Methods 300 cases patients of ASA I~II class voluntary induced abortion of pregnant women were randomly divided into the lornoxicam group(L group),fentanyl(F group) and propofol group(B group),each of 100 cases.Recorded the onset time of anesthesia,operation duration,anesthesia recovery time,amount of propofol.observed before injection and after injection 3min SBP,DBP,HR,SpO2 and intraoperative analgesia,postoperative contractions analgesic effect.And observed adverse reactions during anesthesia and anesthesia complications.Results The onset time of anesthesia,anesthesia recovery time and amount of propofol of L group and F group were better than those of B group,the difference were statistically significant(P0.05);After injection 3min,the level of blood pressure,HR,and SpO2 of three groups were decreased(P0.05),the level of SBP,DBP in B group decreased more significantly(P0.01);The effect of intraoperative analgesia and postoperative contractions analgesic of L group and F group were berrer than those of B group(P0.05),the incidence rate of tongue falling,apnea,postoperative dizziness,nausea and vomiting after surgery in F group were significantly higher than those of L group and B group(P0.05),the incidence rate of restless excitement recovery period in L group and F group was less than that of B group(P0.05).Conclusion Lornoxicam combined with propofol in painless abortion operation is safe and reliable.

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Objective To observe the safety and reliability of lornoxicam combined with propofol in painless abortion operation.Methods 300 cases patients of ASA I~II class voluntary induced abortion of pregnant women were randomly divided into the lornoxicam group(L group),fentanyl(F group) and propofol group(B group),each of 100 cases.Recorded the onset time of anesthesia,operation duration,anesthesia recovery time,amount of propofol.observed before injection and after injection 3min SBP,DBP,HR,SpO2 and intraoperative analgesia,postoperative contractions analgesic effect.And observed adverse reactions during anesthesia and anesthesia complications.Results The onset time of anesthesia,anesthesia recovery time and amount of propofol of L group and F group were better than those of B group,the difference were statistically significant(P0.05);After injection 3min,the level of blood pressure,HR,and SpO2 of three groups were decreased(P0.05),the level of SBP,DBP in B group decreased more significantly(P0.01);The effect of intraoperative analgesia and postoperative contractions analgesic of L group and F group were berrer than those of B group(P0.05),the incidence rate of tongue falling,apnea,postoperative dizziness,nausea and vomiting after surgery in F group were significantly higher than those of L group and B group(P0.05),the incidence rate of restless excitement recovery period in L group and F group was less than that of B group(P0.05).Conclusion Lornoxicam combined with propofol in painless abortion operation is safe and reliable.

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Available abstract

Objective To observe the safety and reliability of lornoxicam combined with propofol in painless abortion operation.Methods 300 cases patients of ASA I~II class voluntary induced abortion of pregnant women were randomly divided into the lornoxicam group(L group),fentanyl(F group) and propofol group(B group),each of 100 cases.Recorded the onset time of anesthesia,operation duration,anesthesia recovery time,amount of propofol.observed before injection and after injection 3min SBP,DBP,HR,SpO2 and intraoperative analgesia,postoperative contractions analgesic effect.And observed adverse reactions during anesthesia and anesthesia complications.Results The onset time of anesthesia,anesthesia recovery time and amount of propofol of L group and F group were better than those of B group,the difference were statistically significant(P0.05);After injection 3min,the level of blood pressure,HR,and SpO2 of three groups were decreased(P0.05),the level of SBP,DBP in B group decreased more significantly(P0.01);The effect of intraoperative analgesia and postoperative contractions analgesic of L group and F group were berrer than those of B group(P0.05),the incidence rate of tongue falling,apnea,postoperative dizziness,nausea and vomiting after surgery in F group were significantly higher than those of L group and B group(P0.05),the incidence rate of restless excitement recovery period in L group and F group was less than that of B group(P0.05).Conclusion Lornoxicam combined with propofol in painless abortion operation is safe and reliable.

Key concepts: Medicine, Propofol, Anesthesia, Fentanyl, Group B, Lornoxicam, Analgesic, Vomiting

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