Influences of comprehensive therapy of replenishing qi,nourishing yin and activating blood circulation on urinary albumin excretion rate and middle-term and long-term curative effects in patients with diabetic nephropathy

Objective To observe the Influences of comprehensive therapy of replenishing qi,nourishing yin and activating blood circulation on urinary albumin excretion rate(UAER) and middle-term and long-term curative effects in patients with diabetic nephropathy(DN).Methods All DN patients(n=120) were randomly divided into treatment group(n=60) and control group(n=60).The control group was given present therapy and treatment group,decoction of Chinese medicinal with actions of replenishing qi,nourishing yin and activating blood circulation besides present therapy.One therapeutic course was two months and the patients were followed up on the 6th month.The level of UAER was detected before and after treatment and during follow-up on the 6th months.The curative effect on UAER and comprehensive curative effect on UAER and symptoms were reviewed 2 months after treatment and during follow-up on the 6th months.The difference in middle-term and long-term curative effects was compared between two groups 2 months after treatment.Results In treatment group UAER decreased significantly(P0.01).The total effective rate was 68.42%,and 52.63% after 6-month follow-up,which had significant and statistical difference compared with control group(P0.01).The review of comprehensive curative effect showed that the total effective rate was 54.39% in treatment group two months after treatment,and 52.63% after 6-month follow-up,which had significant and statistical difference compared with control group(P0.01).Conclusion The comprehensive therapy of replenishing qi,nourishing yin and activating blood circulation can significantly decrease UAER,in DN patients.The curative effect of comprehensive therapy is better than that of present therapy and its middle-term and long-term curative effects are stable.