Traditional Chinese medicine and Western medicine treatment of dry eye in primary Sjgren's syndrome

Objective To observe the therapeutic effects of Traditional Chinese medicine(TCM) combined with Western medicine in the treatment of dry eye in primary Sjogren's syndrome.Methods A Case-control study was employed.110 patients(220 eyes) were averagely divided into two groups,55 cases(110 eyes) in each group.The control group were treated with Hypromellose 2910,Dextran 70 and Glycerol eye drops,recombinant bovine basic fibroblast growth factor eye gel,tarsal massage therapy.The treatment group received the same treatment as the control group,additionally drunk traditional Chinese medicine Runmufengye soup.The dry eye symptom scores,tear film break-up time,Schirmer I test under no topical anesthesia and corneal fluorescein staining were observed and analyzed.Results There was no statistically significant difference in dry eye symptoms score,tear film break-up time,Schirmer I test,corneal fluorescein staining score between the treatment group and control group before treatment(all P 0.05).After treatment of 1 weeks,4 weeks,8 weeks,each index improved over time in the two groups,and there were statistical differences compared with pre-treatment except for 1 week of the control group(all P 0.05).The therapeutic effects of the treatment group were better than those of the control group(all P0.05).Conclusion The effect of integrated traditional Chinese medicine and Western medicine treatment can concordance between the outside and the inside.It was obviously better than that of the Western medicine treatment in improving symptoms and clinical signs of dry eye in primary Sjogren' s syndrome.