2008•The Journal of Clinical PsychiatryRequires access

Accessorial effects of quetiapine in the treatment of senile depression

Wang Guoqian

Abstract

Objective:To study the efficacy and safety of low-dose quetiapine combined with citalopram in the treatment of senile depression. Method:Fifty-six elderly patients with depression were divided into conmbined group and single group randomly.All subjects were assessed with Hamilton rating scale for depression(HAMD),clinical global impression(CGI),Asberg rating scale for side effects. Results:The therapeutic effect of quetiapine combined citalopram was significantly better than that of citalopram group(P 0.05).There was no significant difference of score of Asberg rating scale for side effects between the two groups(P 0.05). Conclusion:Combined treatment with low dose quetiapine combined citalopram for depression in the elderly is safe and treatment effect is better than that of citalopram only.

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Key concepts: Citalopram, Quetiapine, Clinical Global Impression, Hamd, Rating scale, Depression (economics), Psychology, Internal medicine