2014The Chinese Journal of Clinical PharmacologyRequires access

Relationship between the high sensitivity C reactive protein level and the situation of the acute cerebral infarction

Zheng Jian-qion

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Abstract

Objective To investigate the relationship between the serum high-sensitivity C-reactive protein level and the situation of the acute cerebral infarction.Methods The trial group was made up of 151 diagnosed patients with acute cerebral infarction in our hospital and in accordance with the degree of neurological deficit score,they were divided into light,medium and heavy-duty groups.Patients in the trial group were given intravenous dextran 250 mL for 7 consecutive days,Danhong injection 250 mL for 14 days,5% sodium bicarbonate 250 mL for 3 consecutive days,and depending on the patient 's condition,no more than 12,500 units of heparin were given.The control group were 151 random samples from the hospital medical center health personnel.The serum high-sensitivity C-reactive protein,D-dimer and low-density lipoprotein-C(LDL-C) level monitoring in both groups were carried out.Then the two groups were compared.The relationship between serum high-sensitivity C-reactive protein level and severity of acute cerebral infarction was analyzed.Results The positive rate and serum levels with serum hypersensitive C-reactive protein and D-dimer in patients with acute cerebral infarction were higher than those of the control group,with statistical difference(P 0.05).Hs CRP and nervous system damage score were high positive correlation(P 0.05).D-dimer level score was positively correlated with nervous system damage(P 0.05).Conclusion The high sensitivity C-reactive protein level can reflect the incidence and development of cerebral disease independently,and the disease associated with prognosis and close monitoring of high sensitivity C-reactive protein level on the prognosis of significance.

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Objective To investigate the relationship between the serum high-sensitivity C-reactive protein level and the situation of the acute cerebral infarction.Methods The trial group was made up of 151 diagnosed patients with acute cerebral infarction in our hospital and in accordance with the degree of neurological deficit score,they were divided into light,medium and heavy-duty groups.Patients in the trial group were given intravenous dextran 250 mL for 7 consecutive days,Danhong injection 250 mL for 14 days,5% sodium bicarbonate 250 mL for 3 consecutive days,and depending on the patient 's condition,no more than 12,500 units of heparin were given.The control group were 151 random samples from the hospital medical center health personnel.The serum high-sensitivity C-reactive protein,D-dimer and low-density lipoprotein-C(LDL-C) level monitoring in both groups were carried out.Then the two groups were compared.The relationship between serum high-sensitivity C-reactive protein level and severity of acute cerebral infarction was analyzed.Results The positive rate and serum levels with serum hypersensitive C-reactive protein and D-dimer in patients with acute cerebral infarction were higher than those of the control group,with statistical difference(P 0.05).Hs CRP and nervous system damage score were high positive correlation(P 0.05).D-dimer level score was positively correlated with nervous system damage(P 0.05).Conclusion The high sensitivity C-reactive protein level can reflect the incidence and development of cerebral disease independently,and the disease associated with prognosis and close monitoring of high sensitivity C-reactive protein level on the prognosis of significance.

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Available abstract

Objective To investigate the relationship between the serum high-sensitivity C-reactive protein level and the situation of the acute cerebral infarction.Methods The trial group was made up of 151 diagnosed patients with acute cerebral infarction in our hospital and in accordance with the degree of neurological deficit score,they were divided into light,medium and heavy-duty groups.Patients in the trial group were given intravenous dextran 250 mL for 7 consecutive days,Danhong injection 250 mL for 14 days,5% sodium bicarbonate 250 mL for 3 consecutive days,and depending on the patient 's condition,no more than 12,500 units of heparin were given.The control group were 151 random samples from the hospital medical center health personnel.The serum high-sensitivity C-reactive protein,D-dimer and low-density lipoprotein-C(LDL-C) level monitoring in both groups were carried out.Then the two groups were compared.The relationship between serum high-sensitivity C-reactive protein level and severity of acute cerebral infarction was analyzed.Results The positive rate and serum levels with serum hypersensitive C-reactive protein and D-dimer in patients with acute cerebral infarction were higher than those of the control group,with statistical difference(P 0.05).Hs CRP and nervous system damage score were high positive correlation(P 0.05).D-dimer level score was positively correlated with nervous system damage(P 0.05).Conclusion The high sensitivity C-reactive protein level can reflect the incidence and development of cerebral disease independently,and the disease associated with prognosis and close monitoring of high sensitivity C-reactive protein level on the prognosis of significance.

Key concepts: C-reactive protein, Medicine, Cerebral infarction, Internal medicine, Gastroenterology, D-dimer, Infarction, Incidence (geometry)

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