2012China Modern DoctorRequires access

Analysis of the distribution and drug resistance of Acinetobacter Baumannii in recent three years

Chao Chen

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Abstract

Objective To understand the distribution and drug resistance of Acinetobacter Baumannii in our hospital and to provide every department with the basis of anti-infective treatment and reasonable antibiotic drug use.Methods Routine culture method was used to isolate and culture Acinetobacter Baumannii,Micro-Scan auto SCAN4 was used to identify and test drug sensitivity.Results A total of 178 strains of Acinetobacter Baumannii were isolated from January 2009 to December 2011,there was significant difference in the surveillance rate which showed a rising situation year by year(χ2=165.5, P0.01),it was detected mostly at Intensive Care Unit(43.3%),the unit was increasing year by year;and mostly in sputum(61.2%),the sample type was increasing year by year.except for Imipenem,the resistance rate of 14 types of antibiotics was all more than 60%,Multi-drug resistant(MDR) and pan-drug resistant(PDR) were accounted for 78.6%.There was significant difference in the surveillance rate of pan-drug and Imipenem resistant Acinetobacter Baumannii.Conclusion The resistance condition of Acinetobacter baumannii in clinic is serious,we should strengthen the monitoring of Acinetobacter baumannii resistance and build the effective control measure to infection to prevent from the spread of the Acinetobacter baumannii in hospital.

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Objective To understand the distribution and drug resistance of Acinetobacter Baumannii in our hospital and to provide every department with the basis of anti-infective treatment and reasonable antibiotic drug use.Methods Routine culture method was used to isolate and culture Acinetobacter Baumannii,Micro-Scan auto SCAN4 was used to identify and test drug sensitivity.Results A total of 178 strains of Acinetobacter Baumannii were isolated from January 2009 to December 2011,there was significant difference in the surveillance rate which showed a rising situation year by year(χ2=165.5, P0.01),it was detected mostly at Intensive Care Unit(43.3%),the unit was increasing year by year;and mostly in sputum(61.2%),the sample type was increasing year by year.except for Imipenem,the resistance rate of 14 types of antibiotics was all more than 60%,Multi-drug resistant(MDR) and pan-drug resistant(PDR) were accounted for 78.6%.There was significant difference in the surveillance rate of pan-drug and Imipenem resistant Acinetobacter Baumannii.Conclusion The resistance condition of Acinetobacter baumannii in clinic is serious,we should strengthen the monitoring of Acinetobacter baumannii resistance and build the effective control measure to infection to prevent from the spread of the Acinetobacter baumannii in hospital.

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Available abstract

Objective To understand the distribution and drug resistance of Acinetobacter Baumannii in our hospital and to provide every department with the basis of anti-infective treatment and reasonable antibiotic drug use.Methods Routine culture method was used to isolate and culture Acinetobacter Baumannii,Micro-Scan auto SCAN4 was used to identify and test drug sensitivity.Results A total of 178 strains of Acinetobacter Baumannii were isolated from January 2009 to December 2011,there was significant difference in the surveillance rate which showed a rising situation year by year(χ2=165.5, P0.01),it was detected mostly at Intensive Care Unit(43.3%),the unit was increasing year by year;and mostly in sputum(61.2%),the sample type was increasing year by year.except for Imipenem,the resistance rate of 14 types of antibiotics was all more than 60%,Multi-drug resistant(MDR) and pan-drug resistant(PDR) were accounted for 78.6%.There was significant difference in the surveillance rate of pan-drug and Imipenem resistant Acinetobacter Baumannii.Conclusion The resistance condition of Acinetobacter baumannii in clinic is serious,we should strengthen the monitoring of Acinetobacter baumannii resistance and build the effective control measure to infection to prevent from the spread of the Acinetobacter baumannii in hospital.

Key concepts: Acinetobacter baumannii, Medicine, Imipenem, Drug resistance, Acinetobacter, Intensive care unit, Antibiotics, Microbiology

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