Empirical Study of Complex Prescription Decoction Bushen(补肾方) on Mice Model of Kidney-yang Asthenia

Objective: To investigate the effect of Complex Prescription Decoction Bushen on praxiology of model of kidney-yang asthenia.Method: 60 male Kunming mice were selected and divided into 5 groups randomly,which were blank group,model group,Complex Prescription Decoction Bushen low dose group,midium dose group and high dose group.Each group included 12 mice.Except for blank group,Hydrocortisone Injection were given to the four groups by intraperitoneal injection.At the same time distilled water were given to blank group and model group by intraperitoneal injection,and Complex Prescription Decoction Bushen low dose,middle dose and high dose were given to the other groups by intraperitoneal injection.Administration was executed one time each day and was done ten days successively.The mice's body weight increase rate,autonomic activities times,swimming survival time in low temperature water and wet weights of prostate and samenblase were observed.Result: The sys.exhaustion induced by large dose adrenal cortex hormone was shown in model group.In each group of Complex Prescription Decoction Bushen,body weight increase rate,autonomic activities times,swimming survival time in low temperature water were superior to model group.High dose group of Complex Prescription Decoction Bushen could antagonize the atrophy of prostate and samenblase at equal pace.Conclusion: Complex Prescription Decoction Bushen has effect on body weight,autonomic activities times,swimming survival time and atrophy of prostate and samenblase of model of kidney-yang asthenia induced by large dose adrenal cortex hormone.Complex Prescription Decoction Bushen can invigorate the kidney well.