Clinical analysis on the method of in vitro fertilization in patients with few oocytes retrieved

Objective:To explore the choice of in vitro fertilization(IVF) method and clinical outcome of patients with few oocytes retrieved.Methods:The data of 807 patients with few oocytes retrieved(≤5) who were treated with IVF-ET were analyzed retrospectively.The clinical outcomes of conventional IVF group and intracytoplasmic sperm injection(ICSI) group were compared.Results:The normal fertilization rate and utilization rate of embryos in ICSI group were significantly higher than those in conventional IVF group(P0.05),while the rate of multiple PN was significantly lower than that in conventional IVF group(P0.05).There was no significant difference in the rate of high quality embryos,the implantation rate,the pregnancy rate,the cumulative pregnancy rate,the live-birth rate,the cycle cancellation rate and the complete fertilization failure rate between the two groups,but the implantation rate,the pregnancy rate,the cumulative pregnancy rate and the live-birth rate in IVF group were higher than those in ICSI group.Conclusion:When the number of retrieved oocytes is few,ICSI can increase the normal fertilization rate and utilization rate of embryos,reduce the rate of multiple PN,but it can't improve the clinical pregnancy outcome.Thus,ICSI can't optimize the cycles of patients,ICSI is not recommended for the patients with few oocytes retrieved.