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2008•Inner Mongolia Medical JournalRequires access

A Clinical Analysis of Aripiprazole and Clozapine in Treatment of Schizophrenia

Liyong Yang

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Abstract

Objective:To compare the efficacy and safety between Aripiprazole and Clozapine in treatment of schizophrenia.Method: A hundred patients with schizophrenia were randomly divided into two groups receiving Aripiprazole or Clozapine treatment respectively.The periods of treatment were 6 weeks.The positive and negative symptom scale(PANSS) and treatment emergent symptom scale(TESS) were used to evaluate the efficacy and side effects.Results: The efficacy rate of Aripiprazole was 94%,in which 84% were improved markedly.The efficacy rate of Clozapine was 90%,in which 80% were improved markedly.The PANSS scores in both groups decreased significantly after treatment;there was no significant difference in efficacy between two groups.Aripiprazole had fewer side effects than Clozapine.Conclusions: Aripiprazole is an effective drug for schizophrenia,with few side effects.

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What this paper is about

Objective:To compare the efficacy and safety between Aripiprazole and Clozapine in treatment of schizophrenia.Method: A hundred patients with schizophrenia were randomly divided into two groups receiving Aripiprazole or Clozapine treatment respectively.The periods of treatment were 6 weeks.The positive and negative symptom scale(PANSS) and treatment emergent symptom scale(TESS) were used to evaluate the efficacy and side effects.Results: The efficacy rate of Aripiprazole was 94%,in which 84% were improved markedly.The efficacy rate of Clozapine was 90%,in which 80% were improved markedly.The PANSS scores in both groups decreased significantly after treatment;there was no significant difference in efficacy between two groups.Aripiprazole had fewer side effects than Clozapine.Conclusions: Aripiprazole is an effective drug for schizophrenia,with few side effects.

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Available abstract

Objective:To compare the efficacy and safety between Aripiprazole and Clozapine in treatment of schizophrenia.Method: A hundred patients with schizophrenia were randomly divided into two groups receiving Aripiprazole or Clozapine treatment respectively.The periods of treatment were 6 weeks.The positive and negative symptom scale(PANSS) and treatment emergent symptom scale(TESS) were used to evaluate the efficacy and side effects.Results: The efficacy rate of Aripiprazole was 94%,in which 84% were improved markedly.The efficacy rate of Clozapine was 90%,in which 80% were improved markedly.The PANSS scores in both groups decreased significantly after treatment;there was no significant difference in efficacy between two groups.Aripiprazole had fewer side effects than Clozapine.Conclusions: Aripiprazole is an effective drug for schizophrenia,with few side effects.

Key concepts: Aripiprazole, Clozapine, Medicine, Schizophrenia (object-oriented programming), Clinical efficacy, Side effect (computer science), Internal medicine, Negative symptom

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