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2010•Junshi Yixue Kexueyuan yuankanRequires access

Expression of cyclooxygenase-1 in ovarian cancer and its significance

Qiong Wu

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Abstract

Objective To explore the expression of cyclooxygenase-1 in ovarian cancer and its significance.Methods Expression of COX-1 and CA125 was detected by immunohistochemistry in 37 cases of ovarian cancer and 31 cases of ovarian cyst.The serum level of COX-1 and CA125 was tested in 40 cases of ovarian cancer and 31 cases of ovarian cyst and 60 healthy volunteers by ELISA.Results The positive expression of COX-1 and CA125 was 78% and 57% in ovarian cancer and 3% and 7% in ovarian cyst,respectively.The expression of COX-1 and CA125 was 65% and 93% at the serum level.Conclusion Expression of COX-1 could act as an auxiliary diagnostic criterion in ovarian carcinoma.

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What this paper is about

Objective To explore the expression of cyclooxygenase-1 in ovarian cancer and its significance.Methods Expression of COX-1 and CA125 was detected by immunohistochemistry in 37 cases of ovarian cancer and 31 cases of ovarian cyst.The serum level of COX-1 and CA125 was tested in 40 cases of ovarian cancer and 31 cases of ovarian cyst and 60 healthy volunteers by ELISA.Results The positive expression of COX-1 and CA125 was 78% and 57% in ovarian cancer and 3% and 7% in ovarian cyst,respectively.The expression of COX-1 and CA125 was 65% and 93% at the serum level.Conclusion Expression of COX-1 could act as an auxiliary diagnostic criterion in ovarian carcinoma.

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Available abstract

Objective To explore the expression of cyclooxygenase-1 in ovarian cancer and its significance.Methods Expression of COX-1 and CA125 was detected by immunohistochemistry in 37 cases of ovarian cancer and 31 cases of ovarian cyst.The serum level of COX-1 and CA125 was tested in 40 cases of ovarian cancer and 31 cases of ovarian cyst and 60 healthy volunteers by ELISA.Results The positive expression of COX-1 and CA125 was 78% and 57% in ovarian cancer and 3% and 7% in ovarian cyst,respectively.The expression of COX-1 and CA125 was 65% and 93% at the serum level.Conclusion Expression of COX-1 could act as an auxiliary diagnostic criterion in ovarian carcinoma.

Key concepts: Ovarian cancer, Immunohistochemistry, Medicine, Ovarian carcinoma, Cyclooxygenase, Ovarian cyst, Cancer, Internal medicine

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