Clinical Observation of Chinese and Western Medicine Combination for Primary Nephrotic Syndrome in Children

Objective To explore an effective way to the treatment of primary nephrotic syndrome(PNS) by combining Chinese and Western medicine. Methods We divided 80 cases of PNS in children according to different treatment ways into:Chinese and Western medicine combination group(Group A,40 cases) and Western medicine group(Group B,40 cases) . The serum levels of cholesterol(TC) ,triglycerides(TG) ,high-density lipoprotein cholesterol(HDL-C) and low-density lipoprotein cholesterol(LDL-C) were measured before and after treatment. The curative efficacy and adverse reactions were compared between the two groups. Results The total effective rate of Group A was 95.0%,significantly higher than that(82.5%) of Group B(χ2=4.24,P0.05) . The serum levels of TC,TG,HDL-C and LDL-C in Group A after treatment were higher than those of Group B(t=2.220,t=2.307,t=2.344,t=2.319,P0.05) . The adverse reactions of Group A(6 cases,7.5%) were significantly lower than those of Group B(11.2%)(χ2=3.89,P0.05) . Conclusion The curative effect of Chinese and Western medicine combination in the treatment of children with PNS is superior to that of Western medicine alone.