Clinical research of combination of traditional Chinese medicine and western medicine on the treatment of primary nephrotic syndrome

Objective To investigate the clinical effect of combination of traditional Chinese medicine and western medicine on the treatment of primary nephrotic syndrome (PNS).Methods 248 patients with PNS were divided randomly into two groups. The patients in treatment group (n=124) were treated by combination of traditional Chinese medicine and western medicine.Patients in control group (n=124) were treated by routine western medicine.The course was a month in both groups.The effect was evaluated by observing changes of 24h quantitative of urinary protein,plasma albumin,blood-fat,renal function,FDP and recurrence in two groups before and after treatment.Results There were obvious abnormality in biochemical indicators and FDP before treatment in two groups (P0. 01 or0. 05). The total effective rate in treatment group (96.0 %) was higher than that in control group (75.8 %,P0.05). The incidence rate of side-effects and complication in control group (61.3%) was higher than that in treatment group (19.4%). The recurrent rate in treatment group was lower (4.0%) than that in control group (11.3%).Conclusion Combination of traditional Chinese medicine and western medicine was effective on the treatment of primary nephrotic syndrome.