2014•Zhongguo yaofangRequires access
Clinical Observation of Felodipine Sustained-release Tablets versus Fosinopril Sodium Tablets in the Treatment of Renal Hypertension
Zhou Qing-fen
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Abstract
OBJECTIVE:To compare clinical efficacy and safety of Felodipine sustained-release tablets vs. Fosinopril sodium tablets in the treatment of renal hypertension. METHODS:62 cases of renal hypertension were randomly divided into observation group and control group. Control group was given Fosinopril sodium tablets 10 mg/time,qd;observation group was treated with Felodipine sustained release tablets,5 mg/time,qd. Treatment course of 2 groups lasted for 8 week,and drug dosage was adjusted according to blood pressure during treatment. Clinical efficacy,SF-36 score and ADR were compared between 2 groups. RESULTS:The total effective rate and SF-36 score of observation group were significantly higher than those of control group;there was statistical significance(P0.05);there was no statistical significance in the incidence of ADR between 2 groups(P0.05).CONCLUSIONS:For renal hypertension,Felodipine sustained-release tablets are better than Fosinopril sodium tablets in clinical efficacy and the improvement of life quality,but they have similar safety.