2013Journal of Clinical Medicine in PracticeRequires access

Clinical effects of felodipine sustained-release tablets for renal hypertension and its improvement effect on the quality of life

Bing Liu

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Abstract

Objective To investigate the clinical effects of calcium antagonist felodipine sustainedA1.release tablets in the treatment of renal hypertension and its improvement effect on the quality of life.Methods One hundred patients with renal hypertension were randomly divided into two groups,50 cases in each group.The control group was administered fosinopril sodium tablets,while the observation group recieved felodipine sustainedA1.release tablets.The total therapeutic effect,improvement of blood pressure,urine protein,serum creatinine and quality of life as well as incidence of adverse reactions of patients were compared in both groups.Results The total effectiveness rate in the observation group was obviously higher than that in the control group.The levels of blood pressure,urine protein and serum creatinine after treatment all improved,and the improved degree in the observation group was obviously larger than that in the control group.Each score of the quality of life questionnaire coreA1.30(QLQCA1.30) in the observation group was obviously higher than that in the control group.The incidence of adverse reactions in the observation group had a tendency lower than that in the control group,but there was no significant difference.Conclusion The calcium antagonist felodipine sustainedA1.release tablets in the treatment of renal hypertension has a significant therapeutic effect,and it can significantly improve the quality of life after treatment,so it should be promoted and applied in clinical practice.

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Objective To investigate the clinical effects of calcium antagonist felodipine sustainedA1.release tablets in the treatment of renal hypertension and its improvement effect on the quality of life.Methods One hundred patients with renal hypertension were randomly divided into two groups,50 cases in each group.The control group was administered fosinopril sodium tablets,while the observation group recieved felodipine sustainedA1.release tablets.The total therapeutic effect,improvement of blood pressure,urine protein,serum creatinine and quality of life as well as incidence of adverse reactions of patients were compared in both groups.Results The total effectiveness rate in the observation group was obviously higher than that in the control group.The levels of blood pressure,urine protein and serum creatinine after treatment all improved,and the improved degree in the observation group was obviously larger than that in the control group.Each score of the quality of life questionnaire coreA1.30(QLQCA1.30) in the observation group was obviously higher than that in the control group.The incidence of adverse reactions in the observation group had a tendency lower than that in the control group,but there was no significant difference.Conclusion The calcium antagonist felodipine sustainedA1.release tablets in the treatment of renal hypertension has a significant therapeutic effect,and it can significantly improve the quality of life after treatment,so it should be promoted and applied in clinical practice.

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Available abstract

Objective To investigate the clinical effects of calcium antagonist felodipine sustainedA1.release tablets in the treatment of renal hypertension and its improvement effect on the quality of life.Methods One hundred patients with renal hypertension were randomly divided into two groups,50 cases in each group.The control group was administered fosinopril sodium tablets,while the observation group recieved felodipine sustainedA1.release tablets.The total therapeutic effect,improvement of blood pressure,urine protein,serum creatinine and quality of life as well as incidence of adverse reactions of patients were compared in both groups.Results The total effectiveness rate in the observation group was obviously higher than that in the control group.The levels of blood pressure,urine protein and serum creatinine after treatment all improved,and the improved degree in the observation group was obviously larger than that in the control group.Each score of the quality of life questionnaire coreA1.30(QLQCA1.30) in the observation group was obviously higher than that in the control group.The incidence of adverse reactions in the observation group had a tendency lower than that in the control group,but there was no significant difference.Conclusion The calcium antagonist felodipine sustainedA1.release tablets in the treatment of renal hypertension has a significant therapeutic effect,and it can significantly improve the quality of life after treatment,so it should be promoted and applied in clinical practice.

Key concepts: Felodipine, Medicine, Fosinopril, Blood pressure, Creatinine, Adverse effect, Incidence (geometry), Therapeutic effect

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