Analysis of Clinical Transfusion Reactions in One Large Hospital

Objective To investigate and analyze the ratio and type of clinical transfusion reactions in all blood component infusion in a large hospital.Methods All blood transfusion reactions occurred during Jan.2005 to Feb.2010 were analyzed in our hospital.Results In total 139 852 units of all component blood transfusions cases,143 blood transfusion reactions were observed,and the reaction rate was 0.10%,the highest rate of infusion reaction in all kinds of blood components was whole blood and it showed 0.99%,red blood cell suspension showed 0.14%, frozen plasma showed 0.07%,platelets showed 0.05%,while red cell suspension with leucocytes filtering only showed 0.01%,no transfusion reaction was observed in autologous blood transfusion.When considering the blood transfusion times,the transfusion reaction rates of the 1 U,2 U,3 U,4 U and ≥5 U showed 0.03%,0.06%,0.31%,0.41%,and 1.12% respectively.The main transfusion reaction was non-hemolytic reaction which accounted for 62.94%,and the second one was allergic reactions(accounted for 32.16%).Conclusion Autologous blood transfusion and red blood cells suspension are proved to be more safe blood products in reducing the transfusion reactions,leucocytes filtering red cell suspension is benefit for patient who needs more than 2 U blood transfusion.