Clinical investigation of captopril combined with betaloc in treating patients with congestive heart failure

Objective To investigate the influence of captopril combined with betaloc on the cardiac function in patients with congestive heart failure(CHF).Methods Sixty two patients with CHF were divided into two groups.The control group was treated with conserved therapy including digoxin,diuretics and so on.The therapeutic group was treated by captopril and betaloc on the basis of conserved therapy.Both groups were treated for 12 weeks.Results In the therapeutic group,the heart rate was slowed,and the heart chest ratio was decreased and the left ventricular ejection fraction(LVEF) was increased.All of the differences were significant compared with those before treatment.However in the control group,the difference was not significant before and after treatment.Conclusion Captopril combined with betaloc could decrease heart rate and heart chest ratio and raise LVEF in patients with CHF.