ScholarLens Back to search
2012•Guide of China MedicineRequires access

Determination of VitaminC in Yugan Tablets by HPLC

Wei Wu

Open publisher page 0 citations

Abstract

Objective To establish a method for the determination of Vitamin C in Yugan Tablets.Methods Agilent ZORBAX SB-Aq C18 column(4.6mm× 250mm,5μm) was used as chromatographic column,the acetonitrile-0.1% octane sulfonate,0.1% oxalic acid solution(2∶98) was used as mobile phase,the flow rate was 1.0mL/min.the detection wavelength was set at 249nm.Results The standard curves was linear in the rang of 0.103～0.414μg(r=-1.0000),the average recovery was 99.3%with a RSD of 1.3%.Conclusion The method is simple.accurate and reproducible,and is suitable for quality control of this tablets.

About this research paper

What this paper is about

Objective To establish a method for the determination of Vitamin C in Yugan Tablets.Methods Agilent ZORBAX SB-Aq C18 column(4.6mm× 250mm,5μm) was used as chromatographic column,the acetonitrile-0.1% octane sulfonate,0.1% oxalic acid solution(2∶98) was used as mobile phase,the flow rate was 1.0mL/min.the detection wavelength was set at 249nm.Results The standard curves was linear in the rang of 0.103～0.414μg(r=-1.0000),the average recovery was 99.3%with a RSD of 1.3%.Conclusion The method is simple.accurate and reproducible,and is suitable for quality control of this tablets.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To establish a method for the determination of Vitamin C in Yugan Tablets.Methods Agilent ZORBAX SB-Aq C18 column(4.6mm× 250mm,5μm) was used as chromatographic column,the acetonitrile-0.1% octane sulfonate,0.1% oxalic acid solution(2∶98) was used as mobile phase,the flow rate was 1.0mL/min.the detection wavelength was set at 249nm.Results The standard curves was linear in the rang of 0.103～0.414μg(r=-1.0000),the average recovery was 99.3%with a RSD of 1.3%.Conclusion The method is simple.accurate and reproducible,and is suitable for quality control of this tablets.

Key concepts: Medicine, Chromatography, High-performance liquid chromatography, Content determination, Oxalic acid, Octane, Chemistry, Organic chemistry

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Determination of VitaminC in Yugan Tablets by HPLC — Research Paper | ScholarLens