Antifatigue effect of rhodiol capsule on mice

Objective:To study the antifatigue effect of rhodiol capsules on mice.Methods: The ICR male mice were randomized into four groups,i.e.one control group and three dosage groups of rhodiol capsules.The three treatment groups were given various doses of rhodiol capsules,i.e.0.45 g/kg·bw,0.90 g/kg·bw,1.35 g/kg·bw respectively,for 30 days.The body weight,weight-loaded swimming time,and the levels of serum urea nitrogen,hepatic glycogen and blood lactic acid were determined.Results: The weight-loaded swimming time in medium-dosage group was significantly longer than the control group,and the serum urea nitrogen in medium-dosage group and blood lactic acid in medium/high-dosage group were significantly lower than the control group.Conclusion: Rhodiol capsule can alleviate the exercise-induced fatigue in mice.