A Clinical Analysis About Microvascular Density Determination and Prognosis on Gastric Carcinoma Metastasis

Objective To study the clinical significance of the microvessel density(MVD).Methods The immunohistochemical method were adopted to detect CD34 expression in 42 cases of human gastric cancer patients and the correlation between the expression level and clinical pathological features was analyzed.Analysis of the microvascular density relationship with clinicopathological factors and prognosis.Results MVD in gastric cancer tissue was 40.26 ± 12.6.The beside carcinoma tissue MVD was 21.2 ± 9.12.And in the normal tissue MVD was 12.20 ± 4.21.Gastric cancer tissue microvascular density was higher than that of tissue adjacent to carcinoma and normal tissues,with significant difference.Gastric cancer patients with microvascular density of 5 a survival rate of 21.5,Surial for patients with low MVD group was 43.7,the compared the difference is statistically significant.Conclusions Gastric cancer tissue microvascular density is higher than other stomach tissue.MVD has determining value of the metastasis to some extentand prognosis after gastric cancer resection