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2001•Journal of Clinical CardiologyRequires access

Therapeutic efficacy of carvedilol in essential hypertension

Mingming Gao

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Abstract

Objective:To investigate the hypotensive effect and tolerability of Carvedilol. Method:Sixty eight patients were selected. In which, 30 cases were randomised to receive Carvedilol (n=15, 10～30 mg/d), or Labalol (n=15 100～300 mg/d) and remaining 38 cases received Carvedilol (10～40 mg/d). The study continued for 10 week.Result:The DBP significantly decreased from 2nd week to 10 week after Carvedilol treatment compared with pretreatment and Carvedilol was obviously better than Labalol. A lower incidence of adverse effects was observed. Conclusion:Carvedilol is a safe and effective antihypertension agent in essential hypertension.

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What this paper is about

Objective:To investigate the hypotensive effect and tolerability of Carvedilol. Method:Sixty eight patients were selected. In which, 30 cases were randomised to receive Carvedilol (n=15, 10～30 mg/d), or Labalol (n=15 100～300 mg/d) and remaining 38 cases received Carvedilol (10～40 mg/d). The study continued for 10 week.Result:The DBP significantly decreased from 2nd week to 10 week after Carvedilol treatment compared with pretreatment and Carvedilol was obviously better than Labalol. A lower incidence of adverse effects was observed. Conclusion:Carvedilol is a safe and effective antihypertension agent in essential hypertension.

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Available abstract

Objective:To investigate the hypotensive effect and tolerability of Carvedilol. Method:Sixty eight patients were selected. In which, 30 cases were randomised to receive Carvedilol (n=15, 10～30 mg/d), or Labalol (n=15 100～300 mg/d) and remaining 38 cases received Carvedilol (10～40 mg/d). The study continued for 10 week.Result:The DBP significantly decreased from 2nd week to 10 week after Carvedilol treatment compared with pretreatment and Carvedilol was obviously better than Labalol. A lower incidence of adverse effects was observed. Conclusion:Carvedilol is a safe and effective antihypertension agent in essential hypertension.

Key concepts: Carvedilol, Medicine, Tolerability, Essential hypertension, Adverse effect, Incidence (geometry), Pharmacology, Internal medicine

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