Related risk factors for postoperative intracranial infections in patients with craniocerebral trauma

OBJECTIVE To explore the risk factors and prevention measures for the postoperative intracranial infections after surgery for craniocerebral trauma so as to prevent and reduce the incidence of the intracranial infections.METHODS The clinical data of 137 patients with postoperative intracranial infections selected from 1643 patients undergoing craniocerebral trauma surgery were retrospectively analyzed.The possible risk factors associated with ICI were firstly analyzed with single factor analysis,and then analyzed with multiple logistic regression method.RESULTS Univariate analysis showed that the age,operation duration,cerebrospinal fluid leakage,ventricle external drainage,pre-operation GCS score and open wound were the risk factors for the postoperative intracranial infections in patients after craniotomy(P0.05).The multivariate logistic regression analysis found that the ventricle external drainage,cerebrospinal fluid leakage and operation duration were the independent high risk factors for intracranial infections after craniotomy.CONCLUSION The intracranial infections after the craniotomy are the combined effect of multiple factors,however,the ventricle external drainage,the cerebrospinal fluid leakage and the operation duration are the independent risk factors for postoperative intracranial infections.It is conducive to reduce the incidence of intracranial infections after the surgery for craniocerebral trauma to take measures in the early stage for preventive treatment of the patients at high risk.