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The Detection and Clinical Significance of Serum Tumor Necrosis Factor-α and Nitric Oxide in non Insulin Dependent Diabetes Mellituria

Fen Zhang

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Abstract

The serum levels of tumor necrosis factor α(TNF α)and nitric oxide (NO) were determined with ELISA and Gress in 76 cases of NIDDM,38 normal subjets.The results were:were the serum TNF α and NO levels in NIDDM were significantly higher than that in of normal controls ( P 0 01).The serum levels of TNF α and NO havn't associated with blood glucose TNF α has correlated with the course of disease,LP (a),LDL and TG.NO hasn't associated with course of disease but has correlated with LP(a),LDL and TG. TNF α also has correlated with its complications The detection of TNF α and NO might be significant observing factors of clinical changes of NIDDM.

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What this paper is about

The serum levels of tumor necrosis factor α(TNF α)and nitric oxide (NO) were determined with ELISA and Gress in 76 cases of NIDDM,38 normal subjets.The results were:were the serum TNF α and NO levels in NIDDM were significantly higher than that in of normal controls ( P 0 01).The serum levels of TNF α and NO havn't associated with blood glucose TNF α has correlated with the course of disease,LP (a),LDL and TG.NO hasn't associated with course of disease but has correlated with LP(a),LDL and TG. TNF α also has correlated with its complications The detection of TNF α and NO might be significant observing factors of clinical changes of NIDDM.

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Available abstract

The serum levels of tumor necrosis factor α(TNF α)and nitric oxide (NO) were determined with ELISA and Gress in 76 cases of NIDDM,38 normal subjets.The results were:were the serum TNF α and NO levels in NIDDM were significantly higher than that in of normal controls ( P 0 01).The serum levels of TNF α and NO havn't associated with blood glucose TNF α has correlated with the course of disease,LP (a),LDL and TG.NO hasn't associated with course of disease but has correlated with LP(a),LDL and TG. TNF α also has correlated with its complications The detection of TNF α and NO might be significant observing factors of clinical changes of NIDDM.

Key concepts: Tumor necrosis factor alpha, Nitric oxide, Internal medicine, Diabetes mellitus, Endocrinology, Tumor necrosis factor α, Medicine, Clinical significance

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The Detection and Clinical Significance of Serum Tumor Necrosis Factor-α and Nitric Oxide in non Insulin Dependent Diabetes Mellituria — Research Paper | ScholarLens