Comparative study on effect of enteral and parentral nutrition in critically ill patients

Objective To evaluate the important effect on critically ill patients with early ,full dosage enteral and parenteral nutrition treatment and the comparement of effects between those treatments. Methods During the June of this year, the 124 critically ill patients in the intensive care unit of our hospital were treated and randomly divided into enteral nutrition group, parentaral nutrition group, mixed nutrition group and control group. Within 24～48 hours after admission, the patients in first three groups were cured with correspond nutrition supply and other treatments. The change of every groups patients’ indexes, such as ALT、Cr、CK-MB、TNT、TP、ALB、PA、HGB and occult blood of vomit, were observed before and 10 days later after treatment. Results The indexes of ALT、Cr、CK-MB、TNT in control group were obviously higher than those in EN、PN and MIX groups(P0.05). There was not significant difference of ALT and Cr in the later three groups before and after treatment(P0.05) , and there was not significant difference of ALT and Cr among these groups,also(P0.05). The indexes of ALB、PA、HGB of patients in EN and MIX groups were more increased than those in PN and control groups(P0.05),and the indexes in PN group were higher than those in control group(P0.05),and there was not significant difference between EN and MIX groups(P0.05). Incidence rate of alimentary tract hemorrhage in control and PN groups were 37%,which was higher than that in MIX group, 10.8%,(P0.05). Otherwise, all of them were higher than incidence rate,6.45%,in EN group(P0.05). Conclusion Malnutrion,low immune function, and so on could been effectively prevented with early nutrition supply on critically ill patients. The treatment with enteral nutrition has more advantage than that with parenteral nutrition or single glucose, which could protect gastrointestinal tract and other important organs、prevent displacement of bacteria and toxin、release infection reaction of whole body and avoid MODS.