The comparative study of enteral nutrition and parenteral nutrition in the treatment of severe acute pancreatitis

Objective To compare the clinical effect of enteral nutrition(EN) and parenteral nutrition(PN) in the treatment of severe acute pancreatitis(SAP). Methods 64 patients with SAP were randomly divided into EN group and PN group with each group of 32 cases,both group receiving conventional treatment,moreover,the PN group was given parenteral nutrition,while the EN group was given enteral nutrition for 14 days.The C-reactive protein(CRP) and relative biochemical criterion were detected at admission and the fourteenth day after treatment.The infective complications,operation rate,hospital stays and mortality rate were observed at the same time. Results CRP and relative biochemical criterion were improved obviously in both groups after treatment(P0.01).Compared with PN group,the EN group had higher serum albumin,lower ALT after treatment(P0.01), but there were not significant differences in other index between both groups(P0.05).The infection rate and hospital stays in EN group were lower than those in PN group(P 0.05 or P0.01),but there were not significant differences in operation rate and mortality rate between both groups(P 0.05). Conclusion Compare with PN support in the treatment of SAP,EN support shows advantages on melioration of nutrition,reduction of complications and shortening of hospital stays.