A clinical control study of cefpodoxime proxetil in treatment of acute bacterial infections

AIM To evaluate the safety and efficacy of cefpodoxime proxetil in the treatment of acute bacterial infections.METHODS One hundred and fifteen patients with bacterial infections disease were divided into 2 groups in random.Fifty-five patients in control group(M 24,F 31,age(43±s 13)year)were treated with cefixime 200 mg,po,bid and 60 patients of trial group(M 35,F 25,age(42±13)year)with cefpodoxime proxetil 100 mg,po,bid;both with a course of 7-12 d.The clinical curative effects,antibacteriological effects and adverse reactions were observed.RESULTS In trial and control groups,the cure rates were 73%and 69%,the efficacy rates were 92%and 91%,and the bacterial clearance rates of both groups were 98%and 94%;and with furthermore drug adverse reactions of 7%and 9%,respectively.There were no statistically significant differences between the results of both groups(P0.05).CONCLUSION Cefpodoxime proxetil is effective and safe in the treatment of acute bacterial infections.