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Clinical Study of Thinprep Cytologic Test Combined with Biopsy Under Colposcpy in Diagnosis of Cervical Squamous in Traepitheilial Lesions

Ou Hai

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Abstract

Objective To investigate the effectiveness of thinprep cytologic test(TCT) combined with biopsy under colposcopy for diagnosis of cervical squamous intraepithelial lesions.Methods 800 suspicious patients were assigned to receive TCT combined with biopsy under colposcopy(TCT group,380 patients)or biopsy under colposcopy randomly (control group,420 patients).Pathologic examination of biopsy sample was used as gold standard.Results The coincidence on diagnosis of cervical lesions between TCT group and pathologic exanmination of biopsy sample was 75.0%(285/380),the coincidence on diagnosis of cervical lesions between control group and pathologic exanmination of biopsy sample was 49.5%(208/420),the difference was significant (P0.01).Conclusion TCT combined with biopsy under colposcopy may be a reliable method to screen and diagnose the precancerosis of cervix.

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Objective To investigate the effectiveness of thinprep cytologic test(TCT) combined with biopsy under colposcopy for diagnosis of cervical squamous intraepithelial lesions.Methods 800 suspicious patients were assigned to receive TCT combined with biopsy under colposcopy(TCT group,380 patients)or biopsy under colposcopy randomly (control group,420 patients).Pathologic examination of biopsy sample was used as gold standard.Results The coincidence on diagnosis of cervical lesions between TCT group and pathologic exanmination of biopsy sample was 75.0%(285/380),the coincidence on diagnosis of cervical lesions between control group and pathologic exanmination of biopsy sample was 49.5%(208/420),the difference was significant (P0.01).Conclusion TCT combined with biopsy under colposcopy may be a reliable method to screen and diagnose the precancerosis of cervix.

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Available abstract

Objective To investigate the effectiveness of thinprep cytologic test(TCT) combined with biopsy under colposcopy for diagnosis of cervical squamous intraepithelial lesions.Methods 800 suspicious patients were assigned to receive TCT combined with biopsy under colposcopy(TCT group,380 patients)or biopsy under colposcopy randomly (control group,420 patients).Pathologic examination of biopsy sample was used as gold standard.Results The coincidence on diagnosis of cervical lesions between TCT group and pathologic exanmination of biopsy sample was 75.0%(285/380),the coincidence on diagnosis of cervical lesions between control group and pathologic exanmination of biopsy sample was 49.5%(208/420),the difference was significant (P0.01).Conclusion TCT combined with biopsy under colposcopy may be a reliable method to screen and diagnose the precancerosis of cervix.

Key concepts: Medicine, Colposcopy, Biopsy, Cytology, Cervix, Gold standard (test), Cervical intraepithelial neoplasia, Radiology

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Clinical Study of Thinprep Cytologic Test Combined with Biopsy Under Colposcpy in Diagnosis of Cervical Squamous in Traepitheilial Lesions — Research Paper | ScholarLens