2006•Journal of clinical and experimental medicineRequires access
The efficiency of thinprep cell test (TCT) combined with biopsy under colposcopy in diagnosis of cervical squamous intraepithelial lesions.
Qiu Hui-n
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Abstract
Objictive To investigate the effectiveness of thinprep cell test(TCT) combined with biopsy under colposcope for diagnosis of cervical squamous intraepithelial lesions(CIN).Methods Five hundred and nineteen suspicious patients were randomly assigned to receive TCT combined with biopsy under colposcope(TCT group,268 patients) or biopsy under colposcope(control group,251 patients).Pathologic examination of biopsy sample was used as gold standard.Results he agreement on diagnosis of cervical lesions between TCT group and pathologic examination of biopsy sample was 72.0%(193/268),The agreement on diagnosis of cervical lesions between control group and pathologic examination of biopsy sample was 50.1%(126/251),the difference was significant(χ~2=388.62,P0.005).Conclusion TCT combined with biopsy under colposcope can significantly improve the diagnostic accuracy of CIN.