Clinical investigation on preventing urinary tract infection by lubricating Chlorhexidine gluconate on the catheter

Objective To discuss of the application of 2% Chlorhexidine lubricating catheter for prevention of catheter-as sociated urinary tract infection.Methods Ninety six patients with indwelling catheter were randomly divided into experiment group and control group using a prospective,randomized controlled analysis method.Patients in experiment group adopted closed drainage with the catheter lubricated by 2% Chlorhexidine gluconate and urine bag according to the aseptic operation principle;control group placed catheter closed drainage urine bag according to the aseptic operation principle and collected specimen at regular intervals for germiculture.Results The positive rates of bacterial culture 3,7,10 days after the retention catheterization in control group were 16.67%,37.50% and 54.17% respectively;and that of experiment group were 2.08%,6.25% and 10.42% respectively.The positive rate of bacterial culture of control group was higher than that of experiment group,and the difference between the two groups was statistically significant(P 0.05).Conclusion Lubricating catheter by 2% Chorhexidine for catheterization can effectively prevent the bacteria from getting through the urethra surrounding mucosa and into the bladder by the outside of ureter,and it is an effective and simple method to prevent early urinary tract infection.