2007Bulletin of Chinese CancerRequires access

Clinical Value of Serum Neuron Specific Enolase in Lung Cancer

Zeng Bo-hang

Open publisher page 0 citations

Abstract

Purpose To investigate the clinical value of serum neuron specific enolase(NSE)in lung cancer.Methods The serum level of NSE in 374 cases with lung cancer,161 cases with benign pulmonary disease and 158 healthy controls was detected by radioimmunoassay.Results The serum NSE in patients with lung cancer was significantly higher than that in patients with benign lung disease and healthy controls(P0.01).The serum NSE level in small-cell lung cancer was the highest,and increased with staging increase in the lung cancer.The serum NSE level in stage Ⅳ/Ⅲ was significantly higher than that in stageⅠ/Ⅱ(P0.01).The prognosis in patients with low level NSE was superior to those with high level NSE.Conclusions NSE may be used as a useful tumor marker in patients with lung cancer.

About this research paper

What this paper is about

Purpose To investigate the clinical value of serum neuron specific enolase(NSE)in lung cancer.Methods The serum level of NSE in 374 cases with lung cancer,161 cases with benign pulmonary disease and 158 healthy controls was detected by radioimmunoassay.Results The serum NSE in patients with lung cancer was significantly higher than that in patients with benign lung disease and healthy controls(P0.01).The serum NSE level in small-cell lung cancer was the highest,and increased with staging increase in the lung cancer.The serum NSE level in stage Ⅳ/Ⅲ was significantly higher than that in stageⅠ/Ⅱ(P0.01).The prognosis in patients with low level NSE was superior to those with high level NSE.Conclusions NSE may be used as a useful tumor marker in patients with lung cancer.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Purpose To investigate the clinical value of serum neuron specific enolase(NSE)in lung cancer.Methods The serum level of NSE in 374 cases with lung cancer,161 cases with benign pulmonary disease and 158 healthy controls was detected by radioimmunoassay.Results The serum NSE in patients with lung cancer was significantly higher than that in patients with benign lung disease and healthy controls(P0.01).The serum NSE level in small-cell lung cancer was the highest,and increased with staging increase in the lung cancer.The serum NSE level in stage Ⅳ/Ⅲ was significantly higher than that in stageⅠ/Ⅱ(P0.01).The prognosis in patients with low level NSE was superior to those with high level NSE.Conclusions NSE may be used as a useful tumor marker in patients with lung cancer.

Key concepts: Enolase, Lung cancer, Medicine, Stage (stratigraphy), Internal medicine, Radioimmunoassay, Lung, Gastroenterology

Related papers

Back to paper searchBrowse research topicsOriginal source
Clinical Value of Serum Neuron Specific Enolase in Lung Cancer — Research Paper | ScholarLens