Clinical Value of Serum Neuron Specific Enolase in Lung Cancer
Zeng Bo-hang
Abstract
Zeng Bo-hang
Abstract
Purpose To investigate the clinical value of serum neuron specific enolase(NSE)in lung cancer.Methods The serum level of NSE in 374 cases with lung cancer,161 cases with benign pulmonary disease and 158 healthy controls was detected by radioimmunoassay.Results The serum NSE in patients with lung cancer was significantly higher than that in patients with benign lung disease and healthy controls(P0.01).The serum NSE level in small-cell lung cancer was the highest,and increased with staging increase in the lung cancer.The serum NSE level in stage Ⅳ/Ⅲ was significantly higher than that in stageⅠ/Ⅱ(P0.01).The prognosis in patients with low level NSE was superior to those with high level NSE.Conclusions NSE may be used as a useful tumor marker in patients with lung cancer.
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Purpose To investigate the clinical value of serum neuron specific enolase(NSE)in lung cancer.Methods The serum level of NSE in 374 cases with lung cancer,161 cases with benign pulmonary disease and 158 healthy controls was detected by radioimmunoassay.Results The serum NSE in patients with lung cancer was significantly higher than that in patients with benign lung disease and healthy controls(P0.01).The serum NSE level in small-cell lung cancer was the highest,and increased with staging increase in the lung cancer.The serum NSE level in stage Ⅳ/Ⅲ was significantly higher than that in stageⅠ/Ⅱ(P0.01).The prognosis in patients with low level NSE was superior to those with high level NSE.Conclusions NSE may be used as a useful tumor marker in patients with lung cancer.
Key concepts: Enolase, Lung cancer, Medicine, Stage (stratigraphy), Internal medicine, Radioimmunoassay, Lung, Gastroenterology