ScholarLens Back to search
2012•China Medicine and PharmacyRequires access

Clinical value of neuron specific enolase in diagnosis of small cell lung cancer

Xiaoru Chen

Open publisher page 1 citations

Abstract

Objective To investigate a serum marker with high sensitivity and specificity in diagnosis of Small Cell Lung Cancer.Methods The serum level of NSE in 96 cases with lung cancer,221 cases with Pulmonary fibrosis and 176 healthy controls was detected by radioimmunoassay.Results The serum NSE in patients with lung cancer was significantly higher than that in patients with Pulmonary fibrosis and healthy controls (P 0.01).The serum NSE level in small-cell lung cancer was the highest,and increased with staging increase in the lung cancer.The serum NSE level in stage Ⅳ /Ⅲ was significantly higher than that in stage Ⅰ /Ⅱ (P 0.01).The prognosis in patients with low level NSE was superior to those with high level NSE.Conclusion NSE may be used as a useful tumor marker in patients with lung cancer.

About this research paper

What this paper is about

Objective To investigate a serum marker with high sensitivity and specificity in diagnosis of Small Cell Lung Cancer.Methods The serum level of NSE in 96 cases with lung cancer,221 cases with Pulmonary fibrosis and 176 healthy controls was detected by radioimmunoassay.Results The serum NSE in patients with lung cancer was significantly higher than that in patients with Pulmonary fibrosis and healthy controls (P 0.01).The serum NSE level in small-cell lung cancer was the highest,and increased with staging increase in the lung cancer.The serum NSE level in stage Ⅳ /Ⅲ was significantly higher than that in stage Ⅰ /Ⅱ (P 0.01).The prognosis in patients with low level NSE was superior to those with high level NSE.Conclusion NSE may be used as a useful tumor marker in patients with lung cancer.

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To investigate a serum marker with high sensitivity and specificity in diagnosis of Small Cell Lung Cancer.Methods The serum level of NSE in 96 cases with lung cancer,221 cases with Pulmonary fibrosis and 176 healthy controls was detected by radioimmunoassay.Results The serum NSE in patients with lung cancer was significantly higher than that in patients with Pulmonary fibrosis and healthy controls (P 0.01).The serum NSE level in small-cell lung cancer was the highest,and increased with staging increase in the lung cancer.The serum NSE level in stage Ⅳ /Ⅲ was significantly higher than that in stage Ⅰ /Ⅱ (P 0.01).The prognosis in patients with low level NSE was superior to those with high level NSE.Conclusion NSE may be used as a useful tumor marker in patients with lung cancer.

Key concepts: Medicine, Enolase, Lung cancer, Stage (stratigraphy), Internal medicine, Radioimmunoassay, Tumor marker, Lung

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Clinical value of neuron specific enolase in diagnosis of small cell lung cancer — Research Paper | ScholarLens