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2009•Unpublished venueRequires access

Effect of Tropisetron on Nausea and Vomiting During Patient Controlled Intravenous Analgesia with Morphine

Wei Bing-hua

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Abstract

Objective:To investigate the effects of Tropisetron with different administrations on postoperative nausea and vomiting(PONV) during patient-controlled intravenous analgesia with Morphine after abdominal surgery.Methods:120 cases of ASA I-Ⅱelective abdominal surgery were randomly divided into four groups: Morphine group(groupA),group Dropridol(groupB),group Tropisetron of 2.5mg(groupC),group Tropisetron of 5mg(groupD).The efficacy of analgesia and the numbers of patients with PONV,the scores of PONV and side effects in 6,12,24,48hrs after PCIA were investigated respectivel.Results:In groups B,C and D,the incidence of nausea and vomiting was significantly lower than in group A,especially in group D(P 0.01).Conclusions:Tropisetron can safely and effectly prevent PONV in PCIA with Morphine.Tropisetron of 2.5mg had less side effects.

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Objective:To investigate the effects of Tropisetron with different administrations on postoperative nausea and vomiting(PONV) during patient-controlled intravenous analgesia with Morphine after abdominal surgery.Methods:120 cases of ASA I-Ⅱelective abdominal surgery were randomly divided into four groups: Morphine group(groupA),group Dropridol(groupB),group Tropisetron of 2.5mg(groupC),group Tropisetron of 5mg(groupD).The efficacy of analgesia and the numbers of patients with PONV,the scores of PONV and side effects in 6,12,24,48hrs after PCIA were investigated respectivel.Results:In groups B,C and D,the incidence of nausea and vomiting was significantly lower than in group A,especially in group D(P 0.01).Conclusions:Tropisetron can safely and effectly prevent PONV in PCIA with Morphine.Tropisetron of 2.5mg had less side effects.

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Available abstract

Objective:To investigate the effects of Tropisetron with different administrations on postoperative nausea and vomiting(PONV) during patient-controlled intravenous analgesia with Morphine after abdominal surgery.Methods:120 cases of ASA I-Ⅱelective abdominal surgery were randomly divided into four groups: Morphine group(groupA),group Dropridol(groupB),group Tropisetron of 2.5mg(groupC),group Tropisetron of 5mg(groupD).The efficacy of analgesia and the numbers of patients with PONV,the scores of PONV and side effects in 6,12,24,48hrs after PCIA were investigated respectivel.Results:In groups B,C and D,the incidence of nausea and vomiting was significantly lower than in group A,especially in group D(P 0.01).Conclusions:Tropisetron can safely and effectly prevent PONV in PCIA with Morphine.Tropisetron of 2.5mg had less side effects.

Key concepts: Tropisetron, Medicine, Vomiting, Nausea, Anesthesia, Postoperative nausea and vomiting, Morphine, Patient-controlled analgesia

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Effect of Tropisetron on Nausea and Vomiting During Patient Controlled Intravenous Analgesia with Morphine — Research Paper | ScholarLens