2007Laboratory Medicine and ClinicRequires access

Significance of glycated protein determination in monitoring type 2 diabetes mellitus

Huang Jiang-bin

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Abstract

Objective To investigate the clinical significance of HbAlc and glycated serum protein(GSP)determination in monitoring type 2 diabetes mellitus.Methods 167 cases of patients with type 2 diabetes mellitus in our hospital and 120 healthy people were enrolled.Fasting plasma glucose(FPG),2hPG,HbAlc and GSP were examined.Then the results were compared and analyzed statistically.Results Compared with those of healthy control group,FPG,2hPG,HbAlc and GSP in type 2 diabetes mellitus group increased significantly(P0.01).HbAlc was positive correlative to FPG and 2hPG in type 2 diabetes mellitus group.After treatment,there wasn't significant difference of FPG,2hPG,HbAlc and GSP between the two groups(P0.05),but HbAlc alternating level wasn't consistent to that of FPG and 2hPG.Conclusion To examine FPG,2hPG,HbAlc and GSP at the same while is helpful for diagnosis of type 2 diabetes mellitus,control of complications and prognosis monitoring.

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Objective To investigate the clinical significance of HbAlc and glycated serum protein(GSP)determination in monitoring type 2 diabetes mellitus.Methods 167 cases of patients with type 2 diabetes mellitus in our hospital and 120 healthy people were enrolled.Fasting plasma glucose(FPG),2hPG,HbAlc and GSP were examined.Then the results were compared and analyzed statistically.Results Compared with those of healthy control group,FPG,2hPG,HbAlc and GSP in type 2 diabetes mellitus group increased significantly(P0.01).HbAlc was positive correlative to FPG and 2hPG in type 2 diabetes mellitus group.After treatment,there wasn't significant difference of FPG,2hPG,HbAlc and GSP between the two groups(P0.05),but HbAlc alternating level wasn't consistent to that of FPG and 2hPG.Conclusion To examine FPG,2hPG,HbAlc and GSP at the same while is helpful for diagnosis of type 2 diabetes mellitus,control of complications and prognosis monitoring.

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Available abstract

Objective To investigate the clinical significance of HbAlc and glycated serum protein(GSP)determination in monitoring type 2 diabetes mellitus.Methods 167 cases of patients with type 2 diabetes mellitus in our hospital and 120 healthy people were enrolled.Fasting plasma glucose(FPG),2hPG,HbAlc and GSP were examined.Then the results were compared and analyzed statistically.Results Compared with those of healthy control group,FPG,2hPG,HbAlc and GSP in type 2 diabetes mellitus group increased significantly(P0.01).HbAlc was positive correlative to FPG and 2hPG in type 2 diabetes mellitus group.After treatment,there wasn't significant difference of FPG,2hPG,HbAlc and GSP between the two groups(P0.05),but HbAlc alternating level wasn't consistent to that of FPG and 2hPG.Conclusion To examine FPG,2hPG,HbAlc and GSP at the same while is helpful for diagnosis of type 2 diabetes mellitus,control of complications and prognosis monitoring.

Key concepts: Type 2 Diabetes Mellitus, Internal medicine, Medicine, Plasma glucose, Diabetes mellitus, Significant difference, Gastroenterology, Type 2 diabetes

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