2003Unpublished venueRequires access

The Diagnostic Value of Dynamic Helical CT for Breast Diseases

Songling Liu

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Abstract

Objective To evaluate dynamic helical CT scanning in differentiation benign with malignant breast lesions.Materials and Methods CT scanning was performed in 38 females with breast lesions, including carcinoma (n=13), fibroadenoma (n=8) and other benign lesions (n=17). Following plain CT scanning, dynamic enhanced scanning was initiated at 1.5, 3, 7 and 10 min after contrast injection. The enhanced patterns of the lesions were analyzed.Results Significant difference in enhancement percentage at 1.5 and 3 min existed between carcinomas and benign lesions (P0.01). Significant difference in the distribution of time density curve type also existed between malignant and benign lesions (P0.01). 80% benign lesions showed type Ⅰ, while 92.3% malignant lesions showed type Ⅲ. Malignant mass was irregular (46.15%) and ill defined (76.92%) with inhomogeneous enhancement (53.85%), while benign one was round (75%) with regular border (83.33%) and homogeneous enhancement (83.33%). The sensitivity, specificity and accuracy of dynamic helical CT scanning for the breast lesions were 100%, 88% and 92.11%, respectively.Conclusion Although helical CT has the disadvantage of high X ray exposure dose, high cost and adverse reaction due to contrast medium, it is of great value in differentiating benign with malignant breast lesions.

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Objective To evaluate dynamic helical CT scanning in differentiation benign with malignant breast lesions.Materials and Methods CT scanning was performed in 38 females with breast lesions, including carcinoma (n=13), fibroadenoma (n=8) and other benign lesions (n=17). Following plain CT scanning, dynamic enhanced scanning was initiated at 1.5, 3, 7 and 10 min after contrast injection. The enhanced patterns of the lesions were analyzed.Results Significant difference in enhancement percentage at 1.5 and 3 min existed between carcinomas and benign lesions (P0.01). Significant difference in the distribution of time density curve type also existed between malignant and benign lesions (P0.01). 80% benign lesions showed type Ⅰ, while 92.3% malignant lesions showed type Ⅲ. Malignant mass was irregular (46.15%) and ill defined (76.92%) with inhomogeneous enhancement (53.85%), while benign one was round (75%) with regular border (83.33%) and homogeneous enhancement (83.33%). The sensitivity, specificity and accuracy of dynamic helical CT scanning for the breast lesions were 100%, 88% and 92.11%, respectively.Conclusion Although helical CT has the disadvantage of high X ray exposure dose, high cost and adverse reaction due to contrast medium, it is of great value in differentiating benign with malignant breast lesions.

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Available abstract

Objective To evaluate dynamic helical CT scanning in differentiation benign with malignant breast lesions.Materials and Methods CT scanning was performed in 38 females with breast lesions, including carcinoma (n=13), fibroadenoma (n=8) and other benign lesions (n=17). Following plain CT scanning, dynamic enhanced scanning was initiated at 1.5, 3, 7 and 10 min after contrast injection. The enhanced patterns of the lesions were analyzed.Results Significant difference in enhancement percentage at 1.5 and 3 min existed between carcinomas and benign lesions (P0.01). Significant difference in the distribution of time density curve type also existed between malignant and benign lesions (P0.01). 80% benign lesions showed type Ⅰ, while 92.3% malignant lesions showed type Ⅲ. Malignant mass was irregular (46.15%) and ill defined (76.92%) with inhomogeneous enhancement (53.85%), while benign one was round (75%) with regular border (83.33%) and homogeneous enhancement (83.33%). The sensitivity, specificity and accuracy of dynamic helical CT scanning for the breast lesions were 100%, 88% and 92.11%, respectively.Conclusion Although helical CT has the disadvantage of high X ray exposure dose, high cost and adverse reaction due to contrast medium, it is of great value in differentiating benign with malignant breast lesions.

Key concepts: Medicine, Fibroadenoma, Significant difference, Radiology, Homogeneous, Nuclear medicine, Dynamic contrast, Lesion

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