Preparation and Quality Evaluation of Curcumin Liposomes Modified with Vitamin A

Curcumin liposomes modified with vitamin A were prepared by reverse-phase evaporation vesicles.Orthogonal test was adopted to optimize the formulation with encapsulation efficiency and binding rate as the evaluation parameters.Encapsulation efficiency,binding rate,particle size and in vitro release were investigated.The ratio of the liposomes of less than 1.58 μm was 57%.The encapsulation efficiency and vitamin A binding rate of curcumin liposomes modified with vitamin A were 89.3% and 61.3%.