Antiproliferative Effect of Genistein on Human Endometrial Carcinoma Cells HEC-1B in Vitro
Xiaoou Xue
Abstract
Xiaoou Xue
Abstract
Objective To investigate the effect in human endometrial carcinoma cell line HEC-1B induced by Genistein.Methods In vitro experiments,MTT assay was used to determine the cell growth inhibitory rate.Flow cytometry was used to determine the cell apoptosis.Results Genistein could inhibit the growth of HEC-1B in a dose-and time-dependent manner.Genistein could induced the apoptosis of HEC-1B.Conclusions Genistein inhibited HEC-1B.cells growth,and induced the apoptosis of HEC-1B.
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Objective To investigate the effect in human endometrial carcinoma cell line HEC-1B induced by Genistein.Methods In vitro experiments,MTT assay was used to determine the cell growth inhibitory rate.Flow cytometry was used to determine the cell apoptosis.Results Genistein could inhibit the growth of HEC-1B in a dose-and time-dependent manner.Genistein could induced the apoptosis of HEC-1B.Conclusions Genistein inhibited HEC-1B.cells growth,and induced the apoptosis of HEC-1B.
Key concepts: Genistein, Apoptosis, Flow cytometry, In vitro, Cell growth, Cell culture, Chemistry, Cell