Analysis of 6995 renal biopsy

Objective To explore epidemiological characteristics of Henan province kidney disease pathology in order to provide theoretical basis for diagnosis and treatment of kidney diseases. Methods To retrospectively analyse the renal pathological data of 6995 patients in our hospital who had renal biopsy from January 2009 to December 2012. Results( 1) The average age at renal biopsy was 34. 46 ± 16. 71( 1- 93) years old within 6995 patients( male 3636 and female 3359),it mainly occurred in the age group 20- 49 y,gender ratio was 1. 08∶ 1,and the male patients were earlier than the female ones( P =0. 001);( 2) Primary glomerular diseases( PGD) accounted for 66. 30%,secondary glomerular diseases( SGD) for31. 32%,and tubular-interstitial diseases for 2. 37%. The PGD in descending order of incidence were IgA nephropathy( IgAN 40. 34%),Minimal change glomerular disease( MCD 24. 29%) and membranous nephropathy( MN 13. 97%);( 3) The SGN in descending order of incidence were lupus nephritis( LN 34. 73%),Henoch Schonlein purpura nephritis( HSPN 19. 58%),hepatitis B virus-associated nephritis( HBVGN 13. 33%) and atypical membranous nephropathy( 10. 77%);( 4) The glomerular diseases induced by vascular disease in descending order of incidence were ischemic renal injury( 4. 84%),malignant hypertensive renal damage( 3. 47%),benign hypertensive renal arteriosclerosis( 1. 69%) and so forth;( 5) The glomerular diseases induced by metabolic diseases in descending order of incidence were diabetic nephropathy( DN 4. 84%),then,renal amyloidosis( 3. 01%),obesity-related kidney disease( 1. 55%) and so on. Conclusion Renal diseases often happened in young people in Henan province,and PGD was a dominating type in which IgA nephropathy was the most common,and the male patients suffered younger than the female ones. Lupus nephritis was the most common pathological type of SGD which occurred more frequently in female patients.