EXPERIMENTAL OBSERVATION ON DISINFECTION PROPERTY OF DICHLORO-DIMETHYL HYDANTION DISINFECTANT

Objective To study the germicidal effect and toxicity of dichloro-dimethy hydantion disinfectant.Methods The Physicochemical test,suspension quantitative germicidal test and animal test were used to observe its stability,disinfection ability and toxicity.Results The quality percentage of available chlorine in the disinfectant was 37%.The content of available chlorine decreased 1.06% after stored at 54℃ for 14 days.The average killing logarithm value of Bacillus subtilis var.niger spores exposed to this disinfectant containing 6 000 mg/L for 30 min was 5.00.The average killing logarithm values of Escherichia coli,Staphylococcus aurous,Pseudomonas aeruginosa and Candida albicans exposed to this disinfectant containing 300 mg/L for 5 min were 5.00.Its LD50 was 1 875.65 mg/kg(bw)in mice actute oral toxienty test.The resalt was negative in the mouse bone marrow polychromatic erythrocyte micronucleus test.Conclusion This disinfectant is stable and has good germicidal efficacy.On vegetative bacteria,fungi and bacterial spores.It has low toxicity and has no mutagenic effect on mice