Chemotherapy in Advanced Non-small Cell Lung Cancer Analysis of Lymphocyte Subsets
Liu Zhong
Abstract
Liu Zhong
Abstract
Objective: To evaluate chemotherapy in advanced non-small cell lung cancer patients on the lymphocyte subsets.Methods: 60 randomly selected hospital treated patients with advanced non-small cell lung cancer chemotherapy prepared for the experimental group,select the same period another examination of 50 healthy volunteers as control group.Follow-up 6 to 12 months,respectively,using flow cytometry in peripheral blood lymphocyte subsets of both groups were detected count.Results: Compared between the two groups,experimental group were CD3+,CD4+,NK cell number and CD4+ / CD8+ ratio were lower than the control group(P 0.05),while the proportion of CD8+ cells was higher.After chemotherapy,CD3+,CD4+,CD4+ / CD8+,NK higher than those before chemotherapy(P0.05),but CD8+ unchanged(P0.05).Conclusion: Chemotherapy for advanced non-small cell lung cancer can significantly improve the patient's immune function.
A significance statement is not available in the OpenAlex record.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
Objective: To evaluate chemotherapy in advanced non-small cell lung cancer patients on the lymphocyte subsets.Methods: 60 randomly selected hospital treated patients with advanced non-small cell lung cancer chemotherapy prepared for the experimental group,select the same period another examination of 50 healthy volunteers as control group.Follow-up 6 to 12 months,respectively,using flow cytometry in peripheral blood lymphocyte subsets of both groups were detected count.Results: Compared between the two groups,experimental group were CD3+,CD4+,NK cell number and CD4+ / CD8+ ratio were lower than the control group(P 0.05),while the proportion of CD8+ cells was higher.After chemotherapy,CD3+,CD4+,CD4+ / CD8+,NK higher than those before chemotherapy(P0.05),but CD8+ unchanged(P0.05).Conclusion: Chemotherapy for advanced non-small cell lung cancer can significantly improve the patient's immune function.
Key concepts: CD8, Chemotherapy, Lung cancer, Immune system, Medicine, CD3, Lymphocyte, Lymphocyte subsets