2012Xiandai shengwu yixue jinzhanRequires access

Chemotherapy in Advanced Non-small Cell Lung Cancer Analysis of Lymphocyte Subsets

Liu Zhong

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Abstract

Objective: To evaluate chemotherapy in advanced non-small cell lung cancer patients on the lymphocyte subsets.Methods: 60 randomly selected hospital treated patients with advanced non-small cell lung cancer chemotherapy prepared for the experimental group,select the same period another examination of 50 healthy volunteers as control group.Follow-up 6 to 12 months,respectively,using flow cytometry in peripheral blood lymphocyte subsets of both groups were detected count.Results: Compared between the two groups,experimental group were CD3+,CD4+,NK cell number and CD4+ / CD8+ ratio were lower than the control group(P 0.05),while the proportion of CD8+ cells was higher.After chemotherapy,CD3+,CD4+,CD4+ / CD8+,NK higher than those before chemotherapy(P0.05),but CD8+ unchanged(P0.05).Conclusion: Chemotherapy for advanced non-small cell lung cancer can significantly improve the patient's immune function.

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What this paper is about

Objective: To evaluate chemotherapy in advanced non-small cell lung cancer patients on the lymphocyte subsets.Methods: 60 randomly selected hospital treated patients with advanced non-small cell lung cancer chemotherapy prepared for the experimental group,select the same period another examination of 50 healthy volunteers as control group.Follow-up 6 to 12 months,respectively,using flow cytometry in peripheral blood lymphocyte subsets of both groups were detected count.Results: Compared between the two groups,experimental group were CD3+,CD4+,NK cell number and CD4+ / CD8+ ratio were lower than the control group(P 0.05),while the proportion of CD8+ cells was higher.After chemotherapy,CD3+,CD4+,CD4+ / CD8+,NK higher than those before chemotherapy(P0.05),but CD8+ unchanged(P0.05).Conclusion: Chemotherapy for advanced non-small cell lung cancer can significantly improve the patient's immune function.

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Available abstract

Objective: To evaluate chemotherapy in advanced non-small cell lung cancer patients on the lymphocyte subsets.Methods: 60 randomly selected hospital treated patients with advanced non-small cell lung cancer chemotherapy prepared for the experimental group,select the same period another examination of 50 healthy volunteers as control group.Follow-up 6 to 12 months,respectively,using flow cytometry in peripheral blood lymphocyte subsets of both groups were detected count.Results: Compared between the two groups,experimental group were CD3+,CD4+,NK cell number and CD4+ / CD8+ ratio were lower than the control group(P 0.05),while the proportion of CD8+ cells was higher.After chemotherapy,CD3+,CD4+,CD4+ / CD8+,NK higher than those before chemotherapy(P0.05),but CD8+ unchanged(P0.05).Conclusion: Chemotherapy for advanced non-small cell lung cancer can significantly improve the patient's immune function.

Key concepts: CD8, Chemotherapy, Lung cancer, Immune system, Medicine, CD3, Lymphocyte, Lymphocyte subsets

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