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2009•The Chinese Journal of DermatovenereologyRequires access

Observation of the Efficacy of Acitretin Combined with NB-UVB on Generalized Psoriasis Plaque

Cao Bi-lan

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Abstract

Objective To investigate the efficacy of acitretin combined with narrow-band ultravioletB(NB-UVB) in the treatment of patients with psoriasis plaque. Methods A total of 65 patients with psoriasis plaque was randomly divided into treatment group(35 cases) and control group(30 cases). Treatment group was treated with acitretin and NB-UVB,while control group was treated with NB-UVB only. The two groups were both treated for 10 weeks. Results The effective rate was 91.43% in treated group,and 66.67% in control group. There was significant difference between two groups (P0.05). The recurrence rate of the two groups has no significant difference(P0.05). Conclusion Radiation of acitretin combined with NB-UVB is safe and can improve the therapy efficacy significantly for patients with generalized psoriasis plaque.

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What this paper is about

Objective To investigate the efficacy of acitretin combined with narrow-band ultravioletB(NB-UVB) in the treatment of patients with psoriasis plaque. Methods A total of 65 patients with psoriasis plaque was randomly divided into treatment group(35 cases) and control group(30 cases). Treatment group was treated with acitretin and NB-UVB,while control group was treated with NB-UVB only. The two groups were both treated for 10 weeks. Results The effective rate was 91.43% in treated group,and 66.67% in control group. There was significant difference between two groups (P0.05). The recurrence rate of the two groups has no significant difference(P0.05). Conclusion Radiation of acitretin combined with NB-UVB is safe and can improve the therapy efficacy significantly for patients with generalized psoriasis plaque.

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Available abstract

Objective To investigate the efficacy of acitretin combined with narrow-band ultravioletB(NB-UVB) in the treatment of patients with psoriasis plaque. Methods A total of 65 patients with psoriasis plaque was randomly divided into treatment group(35 cases) and control group(30 cases). Treatment group was treated with acitretin and NB-UVB,while control group was treated with NB-UVB only. The two groups were both treated for 10 weeks. Results The effective rate was 91.43% in treated group,and 66.67% in control group. There was significant difference between two groups (P0.05). The recurrence rate of the two groups has no significant difference(P0.05). Conclusion Radiation of acitretin combined with NB-UVB is safe and can improve the therapy efficacy significantly for patients with generalized psoriasis plaque.

Key concepts: Acitretin, Psoriasis, Medicine, Dermatology, Plaque psoriasis, Significant difference, Gastroenterology, Internal medicine

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