Comparision of analgesia with lornoxicam versus tramadol in patients undergoing fracture surgery

[Objective] To compare the effectiveness of lornoxicam and tramadol on the pain after fractural operation. [Methods] This study was carried out in a randomized single-blind control test with 155 patients divided into two groups undergoing fractural operations. Experimental group (77 patients) was administered 16 mg of lornoxicam im. Control group (78 patients) was administered 100 mg of tramadol. Pain was assessed by patients using visual analog scales (VAS) at 1, 2, 4, 6 and 8 hours after using drugs and rate of adverse event was also evaluated. [Results] Lornoxicam had greater analgesic efficacy than tramadol in patients (P 0.05), and caused fewer adverse events than tramadol (3.90% vs 12.82%, P 0.05). [Conclusion] Lornoxicam has more significant analgesic efficacy and fewer adverse events than tramadol after fracture surgery, It suggests that lornoxicam provides a new effective analgesic.