Correlation between TRACP,CTX-1,BACP,BGP levels and BMD in 488 women

Objective:To investigate the correlation between tartrate-resistant acid phosphatase(TRACP),collagen C terminal peptide-Ι(CTX-1),bone specific alkaline phosphatase(BACP),bone gla protein(BGP) levels and bone mineral density(BMD).Methods:The levels of TRACP,CTX-1,BACP and BGP were detected by automatic chemical luminescence immune analyzer and enzyme-labeled immune analyzer;and DTX-200-type bone mineral density detector was used to detect BMD;488 objects were divided into several groups according to the standard of 5-year-old age as a group,SPSS 3.0 software was applied for statistical analysis.Results:There was negative correlation between TRACP,CTX-1 and BMD;the levels of BACP and BGP increased significantly in women aged 50～64 years old,which were negatively correlated with BMD,and the levels began to decline in wome above 65 years old.Conclusion:TRACP,CTX-1,BACP and BGP are important bone metabolism indicators for monitoring the changes of bone mass and early diagnosis of osteoporosis.