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2011•Zhongguo linchuang yixueRequires access

Clinical Observation of Short-Course Moxifloxacin in Treating Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Chu Dejie

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Abstract

Objective:To evaluate the efficacy and safety of moxifloxacin short-course treatment in patients with acute exacerbations of chronic obstructive pulmonary disease(AECOPD).Methods:Atotal of 80 patients were randomly into study group and control group,40 cases in each group.Both a groups were given moxifloxacin intravenously 400 mg once daily.The course of therapy was 5 days for study group and 10 days for control group.The clinical effect of the two groups were observed and compared.Results:The clinical success and bacterial eradication rates were similar between the study group and the control group(all P0.05),while the adverse effect rates was occurred less in study group than in control group(P0.05).Conclusions:Short-course treatment of moxifloxacin is effective and safe in the therapy of AECOPD.

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What this paper is about

Objective:To evaluate the efficacy and safety of moxifloxacin short-course treatment in patients with acute exacerbations of chronic obstructive pulmonary disease(AECOPD).Methods:Atotal of 80 patients were randomly into study group and control group,40 cases in each group.Both a groups were given moxifloxacin intravenously 400 mg once daily.The course of therapy was 5 days for study group and 10 days for control group.The clinical effect of the two groups were observed and compared.Results:The clinical success and bacterial eradication rates were similar between the study group and the control group(all P0.05),while the adverse effect rates was occurred less in study group than in control group(P0.05).Conclusions:Short-course treatment of moxifloxacin is effective and safe in the therapy of AECOPD.

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Available abstract

Objective:To evaluate the efficacy and safety of moxifloxacin short-course treatment in patients with acute exacerbations of chronic obstructive pulmonary disease(AECOPD).Methods:Atotal of 80 patients were randomly into study group and control group,40 cases in each group.Both a groups were given moxifloxacin intravenously 400 mg once daily.The course of therapy was 5 days for study group and 10 days for control group.The clinical effect of the two groups were observed and compared.Results:The clinical success and bacterial eradication rates were similar between the study group and the control group(all P0.05),while the adverse effect rates was occurred less in study group than in control group(P0.05).Conclusions:Short-course treatment of moxifloxacin is effective and safe in the therapy of AECOPD.

Key concepts: Medicine, Moxifloxacin, Pulmonary disease, Exacerbation, Internal medicine, COPD, Acute exacerbation of chronic obstructive pulmonary disease, Adverse effect

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Clinical Observation of Short-Course Moxifloxacin in Treating Acute Exacerbation of Chronic Obstructive Pulmonary Disease — Research Paper | ScholarLens