Quantitative tissue velocity imaging evaluation of left ventricular function in obstructive sleep apean syndrome before uvulopalatopharyngoplasty

Objective To investigate the changes of left ventricular function in patients with obstructive sleep apnea syndrome(OSAS) before modified uvulopalatopharyngoplasty(UPPP).Methods In group A,35 OSAS patients were enrolled,males,aged 21-58 years old,mean age 41.27 years old.In group B,33 healthy volunteers were enrolled,aged 22-55 years old,mean age 39.57 years old,which matched in age and sex with group A,as the control group.All patients were performed by conventional echocardiography and quantitative tissue velocity imaging(QTVI),the parameters of left ventricular structure and function were measured.Results The aortic root diameter(AOD),left ventricular end diastolic dimension(LVEDD),left ventricular posterior wall thickness(LVPWT) and the ratio of early to later transmittal inflow velocity(E/A) measured by conventional echocardiography were significantly different between 2 groups(P 0.05);In mitral annulus,the early diastolic peak velocity(Ve) were decreased and the late diastolic peak velocity(Va) were increased in partial segments,the ratio of Ve/Va were decreased while the peak systolic velocity(Vs) were not changed dramatically(P 0.05).Conclusion It is demonstrated that the QTVI detection could supply referenced basis for clinic in preoperatively and postoperatively.Therefore,mitral annular velocity detecting by QTVI is useful in evaluation of cardiac contractility and relaxation at early stage.