Massive allograft for defects after resection of bone malignant tumors

Objectve To study allograft for defects after bone malignant tumor resection in limb preservation. Methods 130 patients with bone malignant tumor underwent resection following Enneking's system.The types of allograft included 1/2 joint, 1/4 joint, whole bone, partial bone shaft,whole bone allograft+prosthesis,and 1/2 joint+vascularizd bone flap. Internal fixation included a plate+screws, screws, intramedullary nail,and locking intramedullary nail.The results were graded according to Mankin's system as excellent, good, fair,and failure;failure means unsatisfactory. Result The patients were followed up for 6～156 months,with a satisfactory rate of 63.8%.Main complications were infection, non-union and fracture of graft,the rate of complications being 39.2%.The limb preservation rate was 76.3%. Conclusions Massive allograft is a good method for repairing defects after bone malignant tumor resection in limbs. The occurrence of complications is related to surgical stage of tumor, chemotherapy,size of bone allograft,adjacent soft tissue,and internal fixation.