Clinical observation on oxytocin combined with carboprost suppository in reducing postpartum hemorrhage after cesarean section in high risk pregnancy

Objective:To investigate the effect of oxytocin combined with carboprost suppository in reducing postpartum hemorrhage after cesarean section in high risk pregnancy.Methods:Altogether 112 pregnant women at high risk accepted cesarean delivery were randomly divided into two groups.The observing group was 68 patients and the carboprost suppository(1 mg) was taken in uterus immediately after child delivery and oxytocin 20 U was injected at the same time.The control group was 44 patients and oxytocin 20 U was injected in uterus after child delivery.Hemorrhage quantities at 2h and 24 h were investigated in two groups.Results:During operation and at 2 h after operation,the hemorrhage quantity of the carboprost suppository group was reduced significantly and the incidence of postpartum hemorrhage was significantly less than that of the group injected oxytocin(P0.05).Conclusion:The combination of intravenous oxytocin with carboprost suppository is highly effective to reduce hemorrhage and prevent postpartum hemorrhage after cesarean delivery in high risk pregnancy with the advantages of convenience,quickness,safety and less adverse reactions,which is worth to be popularized in clinical practice.