Tian Min
Abstract
Based on the result of QSAR which was studied among a series of triazole antifungal agents,11 new compounds were designed and synthesized,and they were identified with MS,IR, 1H NMR.Screened in vitro and compared to control compound fluconazole,four of those showed good antifungal activity.
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Based on the result of QSAR which was studied among a series of triazole antifungal agents,11 new compounds were designed and synthesized,and they were identified with MS,IR, 1H NMR.Screened in vitro and compared to control compound fluconazole,four of those showed good antifungal activity.
Key concepts: Chemistry, Fluconazole, Antifungal, Triazole, Combinatorial chemistry, 1,2,4-Triazole, In vitro, Proton NMR